"A Genomic Regulatory Network for Development" (2002), by Eric H. Davidson, et al

In 2002 Eric Davidson [3] and his research team published ?A Genomic Regulatory Network for Development? in Science. The authors present the first experimental verification and systemic description of a gene regulatory network. This publication represents the culmination of greater than thirty years of work on gene regulation [4] that began in 1969 with ?A Gene Regulatory Network for Development: A Theory? by Roy Britten and Davidson. The modeling of a large number of interactions in a gene network had not been achieved before. Furthermore, this model revealed behaviors of the gene networks that could only be observed at the levels of biological organization [5] above that of the gene.